Book with us
—up to 10% cheaper
than on Booking.com
Check rooms and rates
From161US$ /night
Check-in
13Oct2025Select date
Check-out
14Oct2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

220 North Main Street, Greenville, South Carolina, United States, 29601

Situated around a 5-minute walk from Reedy River, the luxury Hyatt Regency - Greenville hotel offers 325 rooms. Located a few moments from The Children's Museum of the Upstate, the 3-star hotel has an American restaurant as well as a sundeck, a shared lounge, and various recreational opportunities onsite.

Location

Guests can access McPherson Park 1 km from the unique hotel, while Centre Stage is 700 metres away. From the Hyatt Regency Greenville it will take 14 minutes to walk to Falls Park on the Reedy.

The accommodation is also not far from the Reedy River. Hyatt Regency - Greenville hotel is ideally located in Greenville near Piazza Bergamo.

The hotel is 800 metres from Greenville County Art Museum train station, while Greenville-Spartanburg International airport is 24 minutes' drive away.

Rooms

This smoke-free property offers rooms with a seating area featuring an ironing set and an air conditioner, along with a multi-channel TV and pay-per-view channels. They are appointed with a writing table, and also feature coffee/tea making equipment. Providing a shower and a sink, some bathrooms come with towels. Guests can take advantage of views of the city.

Eat & Drink

You can visit Hotel restaurant for lunch and eat American dishes. It offers a variety of fruit desserts that will suit all tastes. There is a lounge bar onsite. It also features a lounge for guests' comfort. You can visit a restaurant situated close by and taste American cuisine.

Leisure & Business

At this award-winning hotel fitness classes and a bowling alley are available for an extra charge. A seasonal outdoor swimming pool as well as a fitness studio highlight the Hyatt Regency. The availability of a beautiful golf course guarantees guests an active stay at this Greenville hotel. Finally, the Hyatt Regency houses a business centre featuring a laptop safe and a photocopier.

View all

Select your room type

The hotel provides many room choices—family rooms, doubles, and pet-friendly suites—with breakfast, free cancellation, and special offers
Kamar kembar superior
Max:
2 persons
29 m² 
Bed options:
2 Single beds
Shower
Bathtub
Check Prices
Kamar queen executive
Max:
2 persons
56 m² 
Bed options:
1 Tempat Tidur Ukuran King
Shower
Bathtub
Check Prices
Kamar queen deluxe
Max:
2 persons
35 m² 
Bed options:
1 Tempat Tidur Ukuran King
Shower
Bathtub
Check Prices
Show all roomsLess

Rates & availability calendar

See current prices and availability for your chosen dates!

Local transport and travel tips

Overview of transport options available

City Centre
Greenville400 m
Airports
Greenville-Spartanburg International (GSP) 22.2 km
Asheville Regional (AVL) 78.1 km
Train
Greenville County Art Museum400 m

Facilities

Hotels feature amenities designed to keep both you and your pet comfortable

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • 24-hour security
  • Luggage storage
  • Lift
  • ATM/Cash machine
  • Vending machines
  • Smoke detectors
  • Electric vehicle charging station
  • Fire extinguishers
  • Key card access
  • Key access

Sports & Fitness

  • Fitness centre
  • Hiking
  • Cycling
  • Bowling
  • Golf course

Guest Parking

  • Electric kettle

Services

  • Valet parking
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Shops/Commercial services
  • Welcome drink

Dining

  • Restaurant
  • Bar/ Lounge area

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cots
  • Children's menu

Spa & Leisure

  • Seasonal outdoor pool
  • Beach umbrellas
  • Sun loungers
  • Live entertainment
  • Sun terrace
  • Leisure/ TV room
  • Jacuzzi

Room features

  • Wi-Fi in rooms
  • Air conditioning
  • Heating
  • Sitting area
  • Terrace
  • Garden furniture
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Bathtub
  • Free toiletries
  • Sink

Self-catering

  • Electric kettle

Media

  • Flat-screen TV
  • Direct dial telephone
  • CD player
  • AM/FM alarm clock

Room decor

  • Curtains
Show more

Hotel location

220 North Main Street, Greenville, South Carolina, United States, 29601
Map view
220 North Main Street, Greenville, South Carolina, United States, 29601
Nearby
Museum
The Children's Museum of the Upstate
500 m
Event hall
Kilgore Lewis House
520 m
Church
Christ Episcopal Church
560 m
14 S Main St
Dark Corner Distillery
310 m
220 N Main St
Noma Square
60 m
Gallery
The Art Cellar
60 m
South Main Street Court Square
Joel Roberts Poinsett
510 m
650 N Academy St Bon Secours Wellness Arena
Greenville Swamp Rabbits
560 m
Gallery
Artists Guild Gallery Of Greenville
20 m
S Main St
Downtown Greenville
520 m
430 N Main St
American Legion
470 m
Restaurants
Antonino Bertolo's Pizza and Wine Bar
30 m
200 N Main St Ste 103
Subway
180 m
225 N Main St
Jersey Mike's Subs
150 m
233 N Main St Suite 10
Menkoi Noodle House
230 m
241 N Main St
Vic's Pizza
180 m
12 E Coffee St
Sully's Steamers
190 m
6 East Washington Street
Groucho's Deli
230 m
20 E Coffee St # SC
Charleston Sports Pub
180 m
15 W Washington St
Want access to early-bird pet-friendly hotel deals?
Access exclusive discounts today!
Check Rates
Check-in
13Oct2025Select date
Check-out
14Oct2025Select date
Rooms and Guests2 Guests, 1 Room