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From161US$ /night
Check-in
28Nov2025Select date
Check-out
29Nov2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

220 North Main Street, Greenville, South Carolina, United States, 29601
Perfect
8.5
8.3
/10
4.2
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The luxury Hyatt Regency - Greenville hotel offers 325 rooms with proximity to Reedy River, which is around a 5-minute walk from the property. Located just 300 metres from Piazza Bergamo and in proximity to McPherson Park, the 3-star hotel features a sundeck, a shared lounge, and various recreational opportunities.

Location

This unique hotel puts you in the centre of Greenville, only 1.1 km from the 32-acre Falls Park on the Reedy. The large Children's Museum of the Upstate is a short way from the Hyatt Regency Greenville, and Centre Stage is 9 minutes' walk away.

The accommodation is 150 m from Project One bus stop and within 800 metres of Greenville County Art Museum train station in Greenville. The hotel is a 24-minute drive from Greenville-Spartanburg International airport.

Rooms

Hyatt Regency - Greenville hotel offers rooms with a seating area featuring an ironing set and an air conditioner, along with a multi-channel TV and pay-per-view channels. They are appointed with a writing table, and also feature coffee/tea making equipment. Providing a shower and a sink, some bathrooms come with towels. Guests can take advantage of views of the city.

Eat & Drink

The American Hotel restaurant serves a variety of dishes, including American cuisine. The lounge bar will set you up nicely for enjoying your stay. The bar area includes a lounge. The smoke-free Hyatt Regency features a restaurant nearby, where guests can enjoy a variety of American cuisine.

Leisure & Business

At this award-winning accommodation fitness classes and a bowling alley are available for an extra charge. A seasonal outdoor swimming pool and a fitness suite will help you stay healthy. Hyatt Regency - Greenville hotel is also convenient for going jogging. Guests can have access to a business centre, and make use of a laptop safe and a photocopier.

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Select your room type

The hotel provides many room choices—family rooms, doubles, and pet-friendly suites—with breakfast, free cancellation, and special offers
Deluxe King Room
2 persons
33 m² 
1 King-size bed
Bathtub
Air conditioning
King Room Accessible Shower Disability Access
2 persons
32 m² 
1 King-size bed
Shower
Air conditioning
King Room Accessible Tub Disability Access
2 persons
32 m² 
1 King-size bed
Bathtub
Air conditioning
Queen Room Two Queen Beds
2 persons
32 m² 
2 King Size Beds
Coffee machine
Bathtub
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Rates & availability calendar

See current prices and availability for your chosen dates!

Local transport and travel tips

Overview of transport options available

City Centre
Greenville400 m
Airports
Greenville-Spartanburg International (GSP) 22.2 km
Asheville Regional (AVL) 78.1 km
Train
Greenville County Art Museum400 m

Facilities

Hotels feature amenities designed to keep both you and your pet comfortable

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • 24-hour security
  • Luggage storage
  • Lift
  • ATM/Cash machine
  • Vending machines
  • Smoke detectors
  • Electric vehicle charging station
  • Fire extinguishers
  • Key card access
  • Key access

Sports & Fitness

  • Fitness centre
  • Hiking
  • Cycling
  • Bowling
  • Golf course

Guest Parking

  • Electric kettle

Services

  • Valet parking
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Shops/Commercial services
  • Welcome drink

Dining

  • Restaurant
  • Bar/ Lounge area

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cots
  • Children's menu

Spa & Leisure

  • Seasonal outdoor pool
  • Beach umbrellas
  • Sun loungers
  • Live entertainment
  • Sun terrace
  • Leisure/ TV room

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Terrace
  • Garden furniture
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries
  • Sink

Self-catering

  • Electric kettle

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Curtains
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Hotel location

220 North Main Street, Greenville, South Carolina, United States, 29601
Map view
220 North Main Street, Greenville, South Carolina, United States, 29601
Nearby
Museum
The Children's Museum of the Upstate
500 m
Event hall
Kilgore Lewis House
520 m
Church
Christ Episcopal Church
560 m
14 S Main St
Dark Corner Distillery
310 m
220 N Main St
Noma Square
60 m
Gallery
The Art Cellar
60 m
South Main Street Court Square
Joel Roberts Poinsett
510 m
650 N Academy St Bon Secours Wellness Arena
Greenville Swamp Rabbits
560 m
Gallery
Artists Guild Gallery Of Greenville
20 m
S Main St
Downtown Greenville
520 m
430 N Main St
American Legion
470 m
Restaurants
Antonino Bertolo's Pizza and Wine Bar
30 m
200 N Main St Ste 103
Subway
180 m
225 N Main St
Jersey Mike's Subs
150 m
233 N Main St Suite 10
Menkoi Noodle House
230 m
241 N Main St
Vic's Pizza
180 m
12 E Coffee St
Sully's Steamers
190 m
6 East Washington Street
Groucho's Deli
230 m
20 E Coffee St # SC
Charleston Sports Pub
180 m
15 W Washington St
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Check-in
28Nov2025Select date
Check-out
29Nov2025Select date
Rooms and Guests2 Guests, 1 Room